Swiss Learning Health System: A national initiative to establish learning cycles for continuous health system improvement.
The health system in Switzerland is taken into account as the most effective on the earth. Nevertheless, to successfully and effectively meet present and future challenges, an infrastructure and tradition are wanted the place the very best proof is systematically made out there and used, and the system evolves on the premise of a continuing trade between analysis, coverage, and apply.
The Swiss Learning Health System institutionalizes this concept as a multistakeholder national initiative to guarantee continuous enchancment by means of ongoing analysis and implementation. This article presents the aims and mechanisms of the Swiss Learning Health System within the context of worldwide initiatives to strengthen health programs and enhance inhabitants health by means of learning cycles.
A nation-wide initiative for mind imaging and medical phenotype knowledge federation in Swiss college reminiscence centres.
The purpose of our nation-wide initiative is to present clinicians intuitive and strong instruments for correct analysis, remedy monitoring and prognosis of cognitive decline that’s primarily based on large-scale multidomain knowledge.We describe a federation framework that permits for statistical evaluation of aggregated mind imaging and medical phenotyping knowledge throughout reminiscence clinics in Switzerland.
IL-8 (-5 to +5) |
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| 5-01377 | CHI Scientific | 4 x 5mg | Ask for price |
Recombinant Human ANXA5/ Annexin 5/ Annexin A5 Protein, His, Yeast-100ug |
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| QP8982-ye-100ug | EnQuireBio | 100ug | EUR 804 |
Recombinant Human ANXA5/ Annexin 5/ Annexin A5 Protein, His, Yeast-10ug |
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| QP8982-ye-10ug | EnQuireBio | 10ug | EUR 369.6 |
Recombinant Human ANXA5/ Annexin 5/ Annexin A5 Protein, His, Yeast-1mg |
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| QP8982-ye-1mg | EnQuireBio | 1mg | EUR 3296.4 |
Recombinant Human ANXA5/ Annexin 5/ Annexin A5 Protein, His, Yeast-200ug |
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| QP8982-ye-200ug | EnQuireBio | 200ug | EUR 1282.8 |
Recombinant Human ANXA5/ Annexin 5/ Annexin A5 Protein, His, Yeast-500ug |
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| QP8982-ye-500ug | EnQuireBio | 500ug | EUR 2164.8 |
Recombinant Human ANXA5/ Annexin 5/ Annexin A5 Protein, His, Yeast-50ug |
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| QP8982-ye-50ug | EnQuireBio | 50ug | EUR 500.4 |
Annexin 1 (ANXA - 1; Ac 2 - 12) |
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| 5-00700 | CHI Scientific | 4 x 5mg | Ask for price |
2',3',5'-triacetyl-5-Azacytidine |
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| B2822-5 | Biovision | EUR 183.6 | |
2',3',5'-triacetyl-5-Azacytidine |
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| C4119-5 | ApexBio | 5 mg | EUR 141.6 |
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Description: 2',3',5'-triacetyl-5-Azacytidine (TAC) is the lead prodrug form of 5-azacytidine which may be rapidly absorbed after oral administration [1]. 5-Azacytidine is an inhibitor of DNA methyltransferase [2]. |
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Histatin 5 |
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| 5-01307 | CHI Scientific | 4 x 1mg | Ask for price |
Necrostatin-5 |
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| 1865-5 | Biovision | EUR 151.2 | |
Aftin-5 |
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| 2575-5 | Biovision | EUR 548.4 | |
CHD-5 |
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| 2693-5 | Biovision | EUR 183.6 | |
5-Iodotubercidin |
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| A3125-5 | ApexBio | 5 mg | EUR 201.6 |
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Description: 5-Iodotubercidin (Itu) is a purine derivative and hence an inhibitor of adenosine kinase with an IC50 value of 26 nM [1]. Adenosine kinase is important in regulating the intracellular and extracellular concentrations of adenosine and hence diverse physiological actions of adenosine [2]. |
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GNF-5 |
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| B1329-5 | Biovision | EUR 170.4 | |
5-ROX |
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| B8212-5 | ApexBio | 5 mg | EUR 234 |
Thrombin Receptor Activator for Peptide 5 (TRAP-5) |
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| A1036-5 | ApexBio | 5 mg | EUR 122.4 |
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Description: Thrombin Receptor Activator for Peptide 5 (TRAP-5),(C30H50N8O7), a peptide with the sequence NH2-Ser-Phe-Leu-Leu-Arg-COOH, MW= 634.76. coagulation factor II (thrombin) receptor is a G protein-coupled receptor involved in the regulation of thrombotic response. |
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[Cit5]-TRAP-5 |
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| 5-00062 | CHI Scientific | 4 x 5mg | Ask for price |
A-VI-5 |
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| 5-00524 | CHI Scientific | 4 x 5mg | Ask for price |
ACTH(5-10) |
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| 5-00605 | CHI Scientific | 4 x 5mg | Ask for price |
Angiotensin (1-5) |
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| 5-00676 | CHI Scientific | 4 x 5mg | Ask for price |
Bradykinin (1-5) |
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| 5-00852 | CHI Scientific | 4 x 5mg | Ask for price |
TRAP-5 amide |
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| 5-02019 | CHI Scientific | 4 x 5mg | Ask for price |
2',5'-Dideoxyadenosine |
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| 2770-5 | Biovision | EUR 288 | |
W-5 hydrochloride |
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| B6277-5 | ApexBio | 5 mg | EUR 139.2 |
5-Nonyloxytryptamine oxalate |
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| B6496-5 | ApexBio | 5 mg | EUR 184.8 |
5'-deoxy Thymidine |
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| C4692-5 | ApexBio | 5 mg | EUR 216 |
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Description: 5'-Deoxy Thymidine has been used as a research tool for antiviral and anticancer studies. 5'-Deoxy Thymidine can be used to study the entry mechanism into human erythrocytes in comparison with other deoxythymidines. |
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Teicoplanin A2-5 |
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| C4938-5 | ApexBio | 5 mg | EUR 1388.4 |
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Description: Teicoplanin A2-5, derived from Actinoplanes teichomyceticus, is a glycopeptide antibiotic which produces a broad spectrum of antibiotic activity against gram-positive bacteria. |
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5-fluoro 203 |
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| C4114-5 | ApexBio | 5 mg | EUR 184.8 |
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Description: 5-fluoro 203 (5F-203) is an antitumor agent and cytotoxic compound that acts as a potent AhR agonist [1][2][3]. The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor involved in regulating xenobiotic-metabolizing enzymes such as cytochrome P450. |
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5-Formylcytosine (5-fC) ELISA Kit |
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| MET-5102-5 | Cell Biolabs | 5 x 96 assays | EUR 2739.6 |
5-Carboxylcytosine (5-caC) ELISA Kit |
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| MET-5103-5 | Cell Biolabs | 5 x 96 assays | EUR 2739.6 |
Boc-5-Ava-OH |
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| 5-04607 | CHI Scientific | 25g | Ask for price |
Boc-5-Ava-OH |
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| 5-04608 | CHI Scientific | 100g | Ask for price |
Fmoc-5-Ava-OH |
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| 5-04609 | CHI Scientific | 5g | Ask for price |
Fmoc-5-Ava-OH |
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| 5-04610 | CHI Scientific | 25g | Ask for price |
Dok- 5 (263 - 275) |
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| 5-01048 | CHI Scientific | 4 x 5mg | Ask for price |
Secretin (5 - 27), porcine |
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| 5-01917 | CHI Scientific | 4 x 1mg | Ask for price |
SH2 Domain Ligand (5) |
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| 5-01929 | CHI Scientific | 4 x 5mg | Ask for price |
Necrosis Inhibitor, Necrox-5 |
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| 2229-5 | Biovision | EUR 738 | |
FAM azide, 5- isomer |
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| A8117-5 | ApexBio | 5 mg | EUR 199.2 |
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Description: FAM azide for Click chemistry labeling. FAM remains one of the most popular fluorescent lablels for various application. Most instruments capable of fluorescence detection, ranging from plate readers to fluorescence microscopes, are able to work in FAM channel. |
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ROX azide, 5- isomer |
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| A8126-5 | ApexBio | 5 mg | EUR 699.6 |
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Description: ROX (rhodamine-X) azide, solid material, and 10 mM solution in DMSO, labeling reagent for Click Chemistry. ROX is a red-emitting rhodamine dye possessing high brightness and fluorescence quantum yield.Pure 5-isomer. |
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TAMRA azide, 5- isomer |
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| A8129-5 | ApexBio | 5 mg | EUR 699.6 |
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Description: TAMRA (TMR, tetramethylrhodamine) azide, solid compound, and 10 mM solution in DMSO, labeling reagent for Click Chemistry. Pure 5-isomer.TAMRA is often used as FRET acceptor for FAM fluorophore. |
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AICA riboside, 5'-phosphate |
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| 9416-5 | Biovision | EUR 183.6 | |
5-Nitroso-8-quinolinol |
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| B2825-5 | Biovision | EUR 130.8 | |
5'-(N-Cyclopropyl)carboxamidoadenosine |
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| C4645-5 | ApexBio | 5 mg | EUR 153.6 |
5-trans U-46619 |
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| C4261-5 | ApexBio | 5 mg | EUR 645.6 |
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Description: 5-trans U-46619 is a minor impurity (2-5%) which variably exists in most commercial preparations of U-46619 [1]. U-46619 is a selective thromboxane A2 agonist involved in inducing platelet aggregation and vascular smooth muscle contraction [2]. |
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2',5'-dideoxy Adenosine |
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| C3993-5 | ApexBio | 5 mg | EUR 226.8 |
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Description: 2',5'-dideoxy Adenosine, a nucleoside analog, is one of the first identified cell-permeable, P-site inhibitors of adenylate cyclase [1]. Adenylyl cyclase is an enzyme with key regulatory roles in almost all cells. |
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Individual Reaction Mix 5 |
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| G065-5 | ABM | 200 reactions | EUR 200.4 |
LV CryoOil 5 ml |
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| LVCO-5 | MiTeGen | 5 ml | EUR 64 |
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Description: LV CryoOil 5 ml |
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Annexin VII (Annexin VII) Antibody |
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| abx230439-100ug | Abbexa | 100 ug | EUR 610.8 |
Annexin VIII (Annexin VIII) Antibody |
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| abx230440-100ug | Abbexa | 100 ug | EUR 577.2 |
Fmoc-Trp(5-OH)-OH |
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| 5-06939 | CHI Scientific | 5g | Ask for price |
Fmoc-Trp(5-OH)-OH |
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| 5-06940 | CHI Scientific | 25g | Ask for price |
Angiotensin 1/2 (1-5) |
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| A1047-5 | ApexBio | 5 mg | EUR 142.8 |
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Description: Angiotensin I/II (1-5) is a peptide (ASP-ARG-VAL-TYR-ILE) that contains the amino acids 1-5 and is converted from Angiotensin I/II.Angiotensin I is formed by the action ofreninonangiotensinogen, an ?-2-globulin with 12 amino acids. |
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Angiotensin 1/2 (5-7) |
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| A1049-5 | ApexBio | 5 mg | EUR 142.8 |
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Description: Angiotensin 1/2 (5-7), (C17H27N5O4), a peptide with the sequence H2N-Ile-His-Pro-OH, MW=365.43. Angiotensin is a peptide hormone that causes vasoconstriction and a subsequent increase in blood pressure. |
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[Pyr5]-Substance P (5-11) |
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| 5-00288 | CHI Scientific | 4 x 5mg | Ask for price |
[Trp3, Arg5]-Ghrelin (1-5) |
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| 5-00313 | CHI Scientific | 4 x 5mg | Ask for price |
beta-Casomorphin (1-5) (bovine) |
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| 5-00475 | CHI Scientific | 4 x 5mg | Ask for price |
Angiotensin I/II (5-8) |
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| 5-00684 | CHI Scientific | 4 x 5mg | Ask for price |
Cholecystokinin Octapeptide (1-5) (desulfated) |
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| 5-00970 | CHI Scientific | 4 x 5mg | Ask for price |
HIV-gp41-Antigenic Peptide 5 |
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| 5-01331 | CHI Scientific | 4 x 1mg | Ask for price |
2-Methyl-5-hydroxytryptamine hydrochloride |
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| 2768-5 | Biovision | EUR 222 | |
2'-O-Methylpseudouridine-5'-Triphosphate |
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| B7993-.5 | ApexBio | 5x100 µl (100 mM) | EUR 16827.6 |
2'-Fluoro-thymidine-5'-Triphosphate |
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| B8035-.5 | ApexBio | 5x100 µl (100 mM) | EUR 2470.8 |
Helioxanthin derivative 5-4-2 |
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| B4700-5 | ApexBio | 5 mg | EUR 819.6 |
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Description: Helioxanthin derivative 5-4-2, an analogue of helioxanthin (ACH126447), is a small-molecule inhibitor of HBV, HSV-1and HSV-2 virus with EC50 values of 0.08 ?M, 0.29 ?M and 0.16 ?M, respectively [1]. |
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3,3',5'-Triiodo-L-thyronine |
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| B2017-5 | Biovision | EUR 274.8 | |
3,3',5'-Triiodo-L-thyronine |
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| C5014-5 | ApexBio | 5 mg | EUR 160.8 |
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Description: 3,3',5'-triiodo-L-thyronine (reverse T3 or rT3) and 3,5,3'-triiodo-L-thyronine (T3) are the metabolism of thyroxine (T4) [1]. 3,3',5'-Triiodo-L-thyronine is thyroid hormone receptors TR? and TR? antagonist [1]. |
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5?-dihydro-11-keto Testosterone |
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| C4317-5 | ApexBio | 5 mg | EUR 703.2 |
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Description: 5?-dihydro-11-keto Testosterone (11KDHT) is a full androgen receptor agonist comparable to dihydrotestosterone (DHT) [1][2][3]. |
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Magnetic Beads (DNA) 5 mL |
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| P920-5 | 101Bio | - | Ask for price |
pLenti-CLDN1 shRNA-5 Plasmid |
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| PVTBAV04867-5 | Lifescience Market | 2 ug | EUR 427.2 |
(5) Base holders and cases |
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| BH-5 | MiTeGen | 5 BOX | EUR 69 |
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Description: (5) Base holders and cases |
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Alleleustrious pmTFP1-Annexin fusion vector Annexin |
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| ABP-FP-TAN | Allele Biotech | 5 ug | Ask for price |
Alleleustrious pWasabi-Annexin fusion vector Annexin |
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| ABP-FP-WAN | Allele Biotech | 5 ug | Ask for price |
Anti-Annexin A10 / Annexin 14 antibody |
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| STJ70117 | St John's Laboratory | 100 µg | EUR 430.8 |
7078D 5 PIPET 5ML STERILE STERILE |
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| 7078D-5 | CORNING | 25/pk | EUR 260.4 |
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Description: Disposable Pipets; Disposable Pipets, Serological, Misc |
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Fmoc-D-Trp(5-Br)-OH |
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| 5-04217 | CHI Scientific | 1g | Ask for price |
Fmoc-D-Trp(5-Br)-OH |
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| 5-04218 | CHI Scientific | 5g | Ask for price |
Fmoc-D-Trp(5-Cl)-OH |
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| 5-04223 | CHI Scientific | 1g | Ask for price |
Fmoc-D-Trp(5-Cl)-OH |
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| 5-04224 | CHI Scientific | 5g | Ask for price |
Fmoc-D-Trp(5-F)-OH |
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| 5-04227 | CHI Scientific | 1g | Ask for price |
Fmoc-D-Trp(5-F)-OH |
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| 5-04228 | CHI Scientific | 5g | Ask for price |
Ac-DL-Trp(5-Br)-OH·DCHA |
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| 5-04229 | CHI Scientific | 1g | Ask for price |
Ac-DL-Trp(5-Br)-OH·DCHA |
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| 5-04230 | CHI Scientific | 5g | Ask for price |
Ac-DL-Trp(5-Cl)-OH·DCHA |
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| 5-04231 | CHI Scientific | 1g | Ask for price |
Ac-DL-Trp(5-Cl)-OH·DCHA |
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| 5-04232 | CHI Scientific | 5g | Ask for price |
Fmoc-2-amino-5-Methoxybenzoic acid |
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| 5-04549 | CHI Scientific | 1g | Ask for price |
Fmoc-2-amino-5-Methoxybenzoic acid |
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| 5-04550 | CHI Scientific | 5g | Ask for price |
Fmoc-3-Ala(5-Thiazoyl)-OH |
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| 5-05361 | CHI Scientific | 1g | Ask for price |
Fmoc-3-Ala(5-Thiazoyl)-OH |
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| 5-05362 | CHI Scientific | 5g | Ask for price |
Beta-Sheet Breaker Peptide iA?5 |
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| A1005-5 | ApexBio | 5 mg | EUR 122.4 |
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Description: Beta-Sheet Breaker Peptide iA?5 (C33H43N5O8), with the sequence H-Leu-Pro-Phe-Phe-Asp-OH, has been shown to inhibit amyloidogenesis in rat brain models. |
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beta-Casomorphin (1-5) amide (bovine) |
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| 5-00476 | CHI Scientific | 4 x 5mg | Ask for price |
cAMP Dependent PK Inhibitor (5-24) |
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| 5-00922 | CHI Scientific | 4 x 1mg | Ask for price |
Kinase Domain of Insulin Receptor (5) |
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| 5-01429 | CHI Scientific | 4 x 1mg | Ask for price |
2'-Fluoro-2'-deoxyadenosine-5'-Triphosphate |
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| B7959-.5 | ApexBio | 5x100 µl (100 mM) | EUR 2470.8 |
2'-Fluoro-2'-deoxycytidine-5'-Triphosphate |
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| B7961-.5 | ApexBio | 5x100 µl (100 mM) | EUR 2470.8 |
2'-Fluoro-2'-deoxyguanosine-5'-Triphosphate |
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| B7962-.5 | ApexBio | 5x100 µl (100 mM) | EUR 2470.8 |
2'-Fluoro-2'-deoxyuridine-5'-Triphosphate |
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| B7963-.5 | ApexBio | 5x100 µl (100 mM) | EUR 2470.8 |
5-(N,N-dimethyl)-Amiloride (hydrochloride) |
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| C3505-5 | ApexBio | 5 mg | EUR 216 |
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Description: 5-(N, N-dimethyl)-Amiloride (hydrochloride), a derivative of amiloride, is an inhibitor of NHE1, NHE2, and NHE3. The Na+/H+ exchanger (NHE) is a protein that has been involved in intracellular pH homeostasis of many mammalian cell types. |
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3-bromo-5-phenyl Salicylic Acid |
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| C4516-5 | ApexBio | 5 mg | EUR 444 |
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Description: Ki: 140 nM for AKR1C1; 1.97 ?M for AKR1C2; 21 ?M for AKR1C3 3-bromo-5-phenyl Salicylic acid is an AKR1C1 inhibitor. |
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5-bromo-3-phenyl Salicylic Acid |
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| C4610-5 | ApexBio | 5 mg | EUR 382.8 |
Nickel NTA Magnetic Agarose Bead (5%) |
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| MagNTANi5-5 | ABTBeads | 5ml suspension | EUR 208.8 |
ICP-MS Multi-Element Solution 5 |
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| CLMS-5 | Scientific Laboratory Supplies | 125ML | EUR 156.18 |
Anti-Pig Whole Serum | RWS-5 |
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| RWS-5 | Immunology Consultants Laboratory | 1.0 mL | EUR 145 |
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Description: Anti-Pig Whole Serum | RWS-5 | Immunology Consultants Laboratory Host: Rabbit Format: Whole Serum Product Type: Primary Antibody Antibody Clonality: Polyclonal |
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Annexin Peptide |
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| 45-007P | ProSci | 0.1 mg | EUR 405.6 |
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Description: (NT) Annexin A11 Peptide |
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Annexin Peptide |
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| 45-008P | ProSci | 0.1 mg | EUR 405.6 |
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Description: (NT) Annexin A2 Peptide |
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Annexin A1 |
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| PR27207 | Neuromics | 2 ug | EUR 465.6 |
Annexin A10 |
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| PR27208 | Neuromics | 5 ug | EUR 229.2 |
Annexin A11 |
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| PR27209 | Neuromics | 5 ug | EUR 229.2 |
Annexin A13 |
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| PR27210 | Neuromics | 2 ug | EUR 229.2 |
Annexin A2 |
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| PR27211 | Neuromics | 5 ug | EUR 229.2 |
Annexin A3 |
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| PR27212 | Neuromics | 5 ug | EUR 229.2 |
Annexin A4 |
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| PR27213 | Neuromics | 2 ug | EUR 229.2 |
Annexin A5 |
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| PR27214 | Neuromics | 5 ug | EUR 229.2 |
Annexin A6 |
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| PR27215 | Neuromics | 2 ug | EUR 229.2 |
Annexin A7 |
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| PR27216 | Neuromics | 5 ug | EUR 229.2 |
Annexin A8 |
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| PR27217 | Neuromics | 5 ug | EUR 229.2 |
CytoSelect Clonogenic Tumor Cell Isolation Kit (5 x 5 preps) |
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| CBA-155-5 | Cell Biolabs | 25 preps | EUR 3894 |
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Description: Many solid tumors contain heterogeneous populations of normal and cancerous cells. Separation of these cell populations is key to an accurate assessment of the true genotypic and phenotypic differences between normal and tumor cells. Our CytoSelect Clonogenic Tumor Cell Isolation Kit uses a proprietary semisolid agar medium to facilitate formation of colonies by cells from solid tumors. Colonies are grown in either a 6-well plate or a 35mm culture dish. These colonies are isolated away from single (i.e. normal) cells by size filtration. The viable cells from these colonies can be easily recovered for further analysis. |
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5-Hydroxytryptamine (5-HT) ELISA Kit |
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| DLR-5-HT-Ge-48T | DL Develop | 48T | EUR 562.8 |
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Description: A competitive inhibition quantitative ELISA assay kit for detection of 5-Hydroxytryptamine (5-HT) in samples from serum, plasma or other biological fluids. |
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5-Hydroxytryptamine (5-HT) ELISA Kit |
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| DLR-5-HT-Ge-96T | DL Develop | 96T | EUR 729.6 |
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Description: A competitive inhibition quantitative ELISA assay kit for detection of 5-Hydroxytryptamine (5-HT) in samples from serum, plasma or other biological fluids. |
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[D-Ala2]- beta-Casomorphin (1-5), bovine |
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| 5-00075 | CHI Scientific | 4 x 5mg | Ask for price |
[D-Pro2]-beta-Casomorphin (1-5) , bovine |
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| 5-00133 | CHI Scientific | 4 x 5mg | Ask for price |
The adaptation and deployment of available knowledge capturing and federation modules is paralleled by developments in ontology, high quality and regulatory management of mind imaging knowledge. Our initiative incentivizes knowledge sharing by means of the frequent useful resource in a manner that gives particular person researcher with entry to large-scale knowledge that surpasses the info acquisition capability of a single centre.
Clinicians profit from fine-grained epidemiological characterization of personal knowledge in contrast with the remainder further to intuitive instruments permitting for computer-based analysis of dementia. Finally, our idea goals at closing the loop between group-level outcomes primarily based on mixture knowledge and particular person analysis by offering illness fashions, that’s, classifiers for neurocognitive problems that can allow the computer-based analysis of particular person sufferers.
The obtained outcomes will inform suggestions on finest medical apply in all related fields specializing in standardization and interoperability of acquired knowledge, privateness safety framework and moral consideration within the context of evolutive pathology.